Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266833 | 0.77 | CYP3A4 (0.64) | CYP1A2CYP3A4CYP2C9HIF1APHLPP2 | |
| SCHEMBL2266835 | 0.77 | CYP3A4 (0.64) | CYP1A2CYP3A4CYP2C9HIF1APHLPP2 | |
| SCHEMBL8910002 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL8910014 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL4278053 | 0.75 | MEN1 (0.68) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL4278058 | 0.75 | MEN1 (0.68) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL4278065 | 0.75 | MEN1 (0.68) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL3282776 | 0.75 | MEN1 (0.61) | HSD17B10MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3282773 | 0.75 | MEN1 (0.61) | HSD17B10MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8538545 | 0.73 | MAPT (0.70) | MEN1KMT2ARAB9ANPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |