Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419561 | 0.89 | GRIK1 (0.45) | CYP3A4CYP2C9GRIK1DPEP1CYP19A1 | |
| SCHEMBL11791657 | 0.85 | LMNA (0.49) | CYP3A4CYP2C9GRIK1DPEP1MAPT | |
| SCHEMBL1174445 | 0.85 | TBXAS1 (0.51) | CYP3A4CYP2C9GRIK1DPEP1MAOA | |
| SCHEMBL10638498 | 0.85 | TBXAS1 (0.51) | CYP3A4CYP2C9GRIK1DPEP1MAOA | |
| SCHEMBL11523193 | 0.78 | F2RL1 (0.49) | CYP3A4CYP19A1MAOATP53MAPT | |
| SCHEMBL10906983 | 0.78 | GRIK1 (0.52) | CYP3A4CYP2C9GRIK1DPEP1RECQL | |
| SCHEMBL1857361 | 0.77 | TP53 (0.61) | CYP19A1MAOAMAOBAPPTP53 | |
| SCHEMBL28079193 | 0.77 | GRIK1 (0.48) | CYP3A4CYP2C9GRIK1DPEP1MAOA | |
| SCHEMBL3793616 | 0.76 | CYP3A4 (0.61) | CYP3A4CYP2C9RECQLTP53MEN1 | |
| SCHEMBL11648495 | 0.76 | TSHR (0.47) | MAOBTP53MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689899-B2 | HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20020019558-A1 | Diamine and acid anhydride | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-14 | — | — | US | disclosed |
| US-6303742-B1 | CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. | KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019558-A1 | Diamine and acid anhydride | CA1, ASIC1, CA4 | CYP3A4 3486/4885CYP2C9 2353/4885GRIK1 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.