Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835326 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL9862906 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL10397026 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL9863162 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL465593 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KMT2AMEN1TSHR | |
| SCHEMBL5932426 | 0.83 | TSHR (0.45) | ALDH1A1CYP3A4KMT2AAKR1C3AKR1C1 | |
| SCHEMBL7225521 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KMT2AMEN1TSHR | |
| SCHEMBL13762614 | 0.83 | HPGD (0.41) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL1199594 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4KMT2AMEN1AKR1C3 | |
| SCHEMBL11505425 | 0.82 | KMT2A (0.42) | ALDH1A1CYP3A4KMT2AAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337196-B1 | REACTION OF KETONE WITH CYANIDE TO FORM CYANOHYDRIN | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2002-01-08 | — | — | US | disclosed |
| EP-0951561-B1 | ENZYMATIC PROCESSES FOR PREPARING (S)-CYANOHYDRINS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2001-08-08 | — | — | EP | disclosed |
| EP-0951561-A1 | ENZYMATIC PROCESSES FOR PREPARING (S)-CYANOHYDRINS | DSM Fine Chemicals Austria GmbH (AT) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998030711-A1 | ENZYMATIC PROCESSES FOR PREPARING (S)-CYANOHYDRINS | DSM CHEMIE LINZ GMBH (AT) | 1998-07-16 | — | — | WO | disclosed |
| US-5493047-A | REACTING OPTICALLY ACTIVE CYANOHYDRIN WITH CARBOXYLIC ACID IN PRESENCE OF DIALKYL AZODICARBOXYLATE AND TRIPHENYLPHOSPHINE TO FORM ESTER OF OPPOSITE CONFIGURATION | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1996-02-20 | — | — | US | disclosed |
| EP-0601237-A1 | Method of preparing optically active cyanohydrin derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1994-06-15 | — | — | EP | disclosed |
| EP-0601632-A1 | Method of preparing optically active cyanohydrin derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1994-06-15 | — | — | EP | disclosed |