Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757157 | 0.86 | SLC6A9 (0.69) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| SCHEMBL7706108 | 0.86 | SLC6A9 (0.69) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7701267 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7706012 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BSLC6A9SLC6A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7702999 | 0.84 | SLC6A9 (0.51) | MTNR1AMTNR1BSLC6A9PPARDFFAR1 | |
| SCHEMBL7698390 | 0.84 | SLC6A9 (0.55) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7706179 | 0.83 | MTNR1A (0.47) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| SCHEMBL7702694 | 0.81 | SLC6A9 (0.53) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7698597 | 0.81 | SLC6A9 (0.55) | MTNR1AMTNR1BSLC6A9PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7698372 | 0.81 | SLC6A9 (0.52) | MTNR1AMTNR1BSLC6A9PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |