Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074262 | 0.85 | MAOB (0.38) | MAOB | |
| SCHEMBL17428430 | 0.85 | MAOB (0.38) | MAOB | |
| SCHEMBL29260847 | 0.77 | MAOB (0.32) | MAOB | |
| SCHEMBL4946673 | 0.77 | CA1 (0.33) | MAOB | |
| SCHEMBL21184213 | 0.77 | MAOB (0.32) | MAOB | |
| SCHEMBL4946678 | 0.77 | CA1 (0.33) | MAOB | |
| SCHEMBL5974388 | 0.76 | IDO1 (0.45) | MAOBIDO1 | |
| SCHEMBL29126087 | 0.76 | ALDH1A1 (0.35) | MAOB | |
| SCHEMBL5974386 | 0.76 | IDO1 (0.45) | MAOBIDO1 | |
| Hydrochloric Acid SCHEMBL29282574 | 0.76 | MAOB (0.31) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337351-B1 | AROMATIC OLEFIN AMINES | TARGACEPT, INC. | 2002-01-08 | — | — | US | disclosed |
| US-6310102-B1 | OXY OR HYDROXY OR NITRO SUBSTITUTED PHENYLALKYLENE AMINE DERIVATIVE USED FOR TREATING A CENTRAL NERVOUS SYSTEM DISORDER CHARACTERIZED BY AN ALTERATION IN NORMAL NEUROTRANSMITTER RELEASE | TARGACEPT, INC. | 2001-10-30 | — | — | US | disclosed |
| US-6262124-B1 | FOR ACTIVATING NICOTINIC CHOLINERGIC RECEPTORS, FOR EXAMPLE, AS AGONISTS OF SPECIFIC NICOTINIC RECEPTOR SUBTYPES; FOR THERAPY OF DYSFUNCTION OF THE CENTRAL AND AUTONOMIC NERVOUS SYSTEMS | TARGACEPT, INC., A CORPORATION OF DELAWARE | 2001-07-17 | — | — | US | disclosed |
| EP-1042274-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000023418-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-04-27 | — | — | WO | disclosed |
| CN-85105193-A | Preparation benzothiophene anti-diarrhoeal agents method | — | 1987-01-28 | — | — | CN | disclosed |