SCHEMBL5074262

SCHEMBL5074262

C(=CC[PH](c1ccccc1)(c1ccccc1)c1ccccc1)C[PH](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.38
CALM1 P0DP23 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17428430 1.00 MAOB (0.38) MAOBCALM1CYP1A2
SCHEMBL29126087 0.89 ALDH1A1 (0.35) MAOB
SCHEMBL29260847 0.85 MAOB (0.32) MAOB
SCHEMBL21184213 0.85 MAOB (0.32) MAOB
SCHEMBL7699281 0.85 MAOB (0.32) MAOB
SCHEMBL4946678 0.85 CA1 (0.33) MAOB
SCHEMBL4946673 0.85 CA1 (0.33) MAOB
SCHEMBL10882646 0.85 TLR8 (0.32)
SCHEMBL5974388 0.84 IDO1 (0.45) MAOB
SCHEMBL5974386 0.84 IDO1 (0.45) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12006553-B2 Companion diagnostics for mitochondrial inhibitors LUNELLA BIOTECH, INC. (CA) 2024-06-11 US disclosed
US-20200255902-A1 COMPANION DIAGNOSTICS FOR MITOCHONDRIAL INHIBITORS LUNELLA BIOTECH, INC. (CA) 2020-08-13 US disclosed
EP-3624897-A1 COMPANION DIAGNOSTICS FOR MITOCHONDRIAL INHIBITORS Lunella Biotech, Inc. (CA) 2020-03-25 EP disclosed
WO-2018213764-A1 COMPANION DIAGNOSTICS FOR MITOCHONDRIAL INHIBITORS LUNELLA BIOTECH, INC. (CA) 2018-11-22 WO disclosed
US-7423168-B2 Reacting allyl starting compound with oxygen nucleophilic agent in presence of transition metal catalyst and monodentate phosphite MITSUBISHI CHEMICAL CORPORATION (JP) 2008-09-09 US disclosed
US-7241857-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-10 US disclosed
US-7173157-B2 Method for producing an allyl compound MITSUBISHI CHEMICAL CORPORATION (JP) 2007-02-06 US disclosed
US-7119222-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-10-10 US disclosed
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-05-18 US disclosed
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2004-07-29 US disclosed
US-20040092777-A1 Method for producing allyl compound MITSUBISHI CHEMICAL CORPORATION (JP) 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 MAOB 2469/4885CALM1 4580/4885CYP1A2 486/4885
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 MAOB 2469/4885CALM1 4580/4885CYP1A2 486/4885
US-20040092777-A1 Method for producing allyl compound CCNT1, APEX1, REV1 MAOB 3382/4885CALM1 3835/4885CYP1A2 1479/4885
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby CCNT1, AOC3, ATL3 MAOB 1689/4885CALM1 4634/4885CYP1A2 385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.