Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7705458 | 0.95 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL28147718 | 0.86 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTMAPK1HDAC1 | |
| SCHEMBL7701432 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL7699286 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL12570978 | 0.83 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2RAB9AMAPTMAPK1 | |
| Dimethylamine SCHEMBL7704008 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| Dimethylamine SCHEMBL7699303 | 0.81 | RAB9A (0.51) | ALDH1A1RAB9AMAPTHDAC1HDAC2 | |
| SCHEMBL31522327 | 0.80 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2RAB9AMAPK1HDAC1 | |
| SCHEMBL31522332 | 0.80 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2RAB9AMAPK1HDAC1 | |
| SCHEMBL1403259 | 0.80 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2RAB9AMAPK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208109-A2 | NUCLEOSIDE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016150-A2 | NUCLEOSIDE ANALOGUES | AMERSHAM PLC (GB) | 2001-03-08 | — | — | WO | disclosed |