Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.46 |
| ▸ | CALML3 | P27482 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694953 | 0.90 | MAOA (0.42) | MAOACALML3 | |
| SCHEMBL7698870 | 0.83 | MAOA (0.42) | MAOACALML3 | |
| SCHEMBL3045106 | 0.79 | MAOA (0.56) | MAOACALML3 | |
| SCHEMBL3043182 | 0.78 | MAOA (0.56) | MAOACALML3 | |
| SCHEMBL7700753 | 0.73 | MAOA (0.53) | MAOACALML3CYP3A4 | |
| SCHEMBL3038619 | 0.72 | MAOA (0.54) | MAOACALML3 | |
| SCHEMBL3048066 | 0.71 | MAOA (0.56) | MAOACALML3 | |
| SCHEMBL3035215 | 0.71 | MAOA (0.53) | MAOACALML3 | |
| SCHEMBL3037799 | 0.71 | MAOA (0.56) | MAOACALML3 | |
| SCHEMBL5744532 | 0.70 | MAOA (0.76) | MAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081469-A1 | OXAZOLIDINONE-SULFOXIMINES AND -SULFILIMINES AS ANTIBIOTICS | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | disclosed |