Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694953 | 0.85 | MAOA (0.42) | MAOACALML3 | |
| SCHEMBL5832800 | 0.77 | MAOA (0.66) | MAOACYP2E1CALML3 | |
| SCHEMBL3323196 | 0.76 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL3323187 | 0.76 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL3323189 | 0.76 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL5833884 | 0.74 | MAOA (0.60) | MAOACYP2E1CALML3 | |
| SCHEMBL7696844 | 0.74 | MAOA (0.73) | MAOACALML3 | |
| SCHEMBL7699299 | 0.73 | MAOA (0.46) | MAOACALML3CYP3A4 | |
| SCHEMBL5834374 | 0.73 | MAOA (0.65) | MAOACYP2E1CALML3 | |
| SCHEMBL7697898 | 0.73 | MAOA (0.53) | MAOACYP2E1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081469-A1 | OXAZOLIDINONE-SULFOXIMINES AND -SULFILIMINES AS ANTIBIOTICS | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | claimed |