Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 15/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734021 | 0.90 | PLA2G2A (0.70) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL7952628 | 0.85 | PLA2G2A (1.00) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL7700846 | 0.84 | PLA2G2A (0.74) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL5437216 | 0.84 | PLA2G2A (0.82) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL8292911 | 0.82 | PLA2G2A (0.78) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL7694484 | 0.82 | PLA2G2A (0.73) | PLA2G2AMAPTPKMALDH1A1KDM4E | |
| SCHEMBL7961660 | 0.80 | PLA2G2A (0.75) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL5605448 | 0.79 | PLA2G2A (0.73) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL290852 | 0.78 | GAA (0.79) | PLA2G2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL3854952 | 0.78 | PLA2G2A (0.60) | PLA2G2AGAAMAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |