Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 17/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961676 | 0.85 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL2001954 | 0.85 | PLA2G2A (0.83) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL7699338 | 0.84 | PLA2G2A (0.73) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL7696968 | 0.82 | PLA2G2A (0.74) | PLA2G2A | |
| SCHEMBL290764 | 0.80 | PLA2G2A (0.67) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL2007975 | 0.79 | PLA2G2A (0.73) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL2002826 | 0.78 | PLA2G2A (0.72) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL9734021 | 0.77 | PLA2G2A (0.70) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL14880137 | 0.77 | MAPT (0.74) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL7961576 | 0.76 | PLA2G2A (0.82) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |