Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629212 | 0.76 | CYP2B6 (0.39) | CYP2B6CYP1A1CYP1A2 | |
| SCHEMBL10668243 | 0.74 | AKR1B1 (0.41) | CYP2B6CYP1A1CYP1A2 | |
| SCHEMBL277664 | 0.73 | CYP2B6 (0.46) | CYP2B6STSCYP1A1CYP1A2CA1 | |
| SCHEMBL30629208 | 0.73 | CYP2B6 (0.38) | CYP2B6CYP1A1CYP1A2 | |
| SCHEMBL29001409 | 0.70 | CYP2B6 (0.41) | CYP2B6STSCYP1A1CYP1A2CA1 | |
| SCHEMBL5543206 | 0.70 | CYP2B6 (0.36) | CYP2B6CYP1A1CYP1A2 | |
| SCHEMBL4648558 | 0.70 | LIPG (0.38) | CYP2B6 | |
| SCHEMBL3076682 | 0.70 | CYP2B6 (0.42) | CYP2B6STSCYP1A1CYP1A2CA1 | |
| SCHEMBL31301918 | 0.70 | CYP2B6 (0.42) | CYP2B6STSCYP1A1CYP1A2CA1 | |
| SCHEMBL30663208 | 0.70 | CYP2B6 (0.42) | CYP2B6STSCYP1A1CYP1A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070507-A2 | GLYCORTICOID RECEPTOR ANTAGONISTS FOR TREATMENT OF DIABETES | ABBOTT LABORATORIES (US) | 2002-09-12 | — | — | WO | disclosed |