Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629212 | 0.86 | CYP2B6 (0.39) | CYP2B6CYP1A2CYP1A1GYS1MTNR1A | |
| SCHEMBL30629173 | 0.76 | CYP2B6 (0.42) | TDP1CYP2B6CYP1A2CYP1A1KDM4E | |
| SCHEMBL1748858 | 0.76 | CYP2B6 (0.42) | TDP1CYP2B6CYP1A2CYP1A1KDM4E | |
| SCHEMBL31027144 | 0.75 | MTNR1A (0.46) | AKR1B1TDP1CYP2B6CYP1A2CYP1A1 | |
| Hydrochloric Acid SCHEMBL6245847 | 0.74 | CYP2B6 (0.41) | TDP1CYP2B6CYP1A2CYP1A1KDM4E | |
| SCHEMBL30629208 | 0.74 | CYP2B6 (0.38) | CYP2B6CYP1A2CYP1A1MTNR1AMTNR1B | |
| SCHEMBL7699360 | 0.74 | CYP2B6 (0.39) | CYP2B6CYP1A2CYP1A1 | |
| SCHEMBL31058480 | 0.74 | CYP2B6 (0.39) | TDP1CYP2B6CYP1A2CYP1A1KDM4E | |
| Succinic Acid SCHEMBL5320883 | 0.74 | PARP1 (0.43) | CYP2B6CYP1A2CYP1A1KDM4EGYS1 | |
| SCHEMBL27641043 | 0.73 | CXCL8 (0.34) | AKR1B1TDP1GYS1CXCL8MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283761-A1 | Chromone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | claimed |