Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13854381 | 0.88 | CYP3A4 (0.50) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL29538101 | 0.86 | CYP3A4 (0.49) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL647965 | 0.86 | CYP3A4 (0.49) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL27169616 | 0.86 | CYP3A4 (0.46) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL29457570 | 0.86 | SHBG (0.61) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL340386 | 0.86 | SHBG (0.61) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL68434 | 0.86 | SHBG (0.61) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL9355691 | 0.84 | ESR1 (0.61) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL2596764 | 0.83 | CYP3A4 (0.44) | SHBGCYP3A4HIF1ACYP2D6ESR1 | |
| SCHEMBL27699975 | 0.83 | CYP3A4 (0.44) | SHBGCYP3A4HIF1ACYP2D6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344505-B1 | Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers | CYTEC INDUSTRIES INC. | 2002-02-05 | — | — | US | disclosed |