Sugi Predict

Sugi Predict / Compounds / SCHEMBL647965

SCHEMBL647965

SCHEMBL647965

CC(C)(C)CC(C)(C)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 3/20 0.49
▸ CYP2D6 P10635 2/20 0.49
▸ HIF1A Q16665 1/20 0.49
▸ SHBG P04278 1/20 0.49
▸ BACE1 P56817 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ ESR1 P03372 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ TP53 P04637 1/20 0.45
▸ PGR P06401 1/20 0.45
▸ ADORA3 P0DMS8 1/20 0.45
▸ AR P10275 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ DRD1 P21728 1/20 0.45
▸ PTGS1 P23219 1/20 0.45
▸ SLC6A2 P23975 1/20 0.45
▸ PDE4A P27815 1/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ CASP1 P29466 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29538101 1.00 CYP3A4 (0.49) CYP3A4CYP2D6HIF1ASHBGBACE1
SCHEMBL21410786 0.95 CYP3A4 (0.46) CYP3A4CYP2D6HIF1ASHBGBACE1
SCHEMBL7699366 0.86 SHBG (0.59) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2
SCHEMBL29538260 0.85 CNR2 (0.51) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2
SCHEMBL29538095 0.85 CYP3A4 (0.45) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2
SCHEMBL22443105 0.85 CYP3A4 (0.38) CYP3A4CYP2D6HIF1ASHBGBACE1
SCHEMBL29538443 0.84 CYP3A4 (0.44) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2
SCHEMBL30105849 0.84 CYP3A4 (0.44) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2
SCHEMBL199860 0.83 SHBG (0.47) CYP3A4CYP2D6HIF1ASHBGBACE1
SCHEMBL29625147 0.83 CYP3A4 (0.43) CYP3A4CYP2D6HIF1ASHBGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109486149-A A kind of PC composite material 广东聚钛新材料有限公司 2019-03-19 — — CN claimed
CN-109456596-A A kind of high-temperature nylon automotive material 惠州市中海源新材料科技有限公司 2019-03-12 — — CN claimed
CN-109135411-A A kind of light guide ink and light guide plate 浙江银鹿新材料有限公司 2019-01-04 — — CN claimed
CN-108753233-A A kind of automobile high-strength silane modified polyether seal glue and preparation method thereof 广州集泰化工股份有限公司 2018-11-06 — — CN claimed
CN-104342254-B High wear-resistant type knitting machine oil composition and application thereof 中国石油化工股份有限公司 2018-01-12 — — CN claimed
US-20240218154-A1 OLEFIN-BASED POLYMER AND PEROXIDE COMPOSITIONS WITH EXCELLENT CURE RESPONSE DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-04 — — US disclosed
CN-110520100-A The manufacturing method of ultraviolet protection overlay film KAO CORP 2019-11-29 — — CN disclosed
CN-110484035-A Coating composition and the hard-coated film for using it SOMAR CORP 2019-11-22 — — CN disclosed
CN-104448981-B Coating composition and hard coating film using same 索马龙株式会社 2019-08-16 — — CN disclosed
CN-110088198-A High flow, ductile poly (aliphatic ester-carbonate) compositions 沙特基础工业全球技术有限公司 2019-08-02 — — CN disclosed
EP-3491034-A1 SILYL-BRIDGED BIS-BIPHENYL-PHENOXY CATALYSTS FOR OLEFIN POLYMERIZATION Dow Global Technologies, LLC (US) 2019-06-05 — — EP disclosed
CN-106459568-B Thermoplastic compounds and laser-welded article SABIC环球技术有限责任公司 2019-04-19 — — CN disclosed
US-6458872-B1 FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 — — US disclosed
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-07-25 — — US disclosed
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-05-30 — — US disclosed
WO-2002042281-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-30 — — WO disclosed
US-6262151-B1 FOR AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 — — US disclosed
US-20010007886-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2001-07-12 — — US disclosed
US-6166218-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 — — US disclosed
US-5977219-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT CYP3A4 58/4885CYP2D6 998/4885HIF1A 2654/4885
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT CYP3A4 58/4885CYP2D6 998/4885HIF1A 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.