Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.53 |
| ▸ | IKBKB | O14920 | 3/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541934 | 0.91 | TARBP2 (0.52) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL30740870 | 0.91 | TARBP2 (0.52) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL20361607 | 0.89 | TARBP2 (0.62) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL21541928 | 0.87 | TARBP2 (0.66) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL21541930 | 0.87 | TARBP2 (0.64) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL21541933 | 0.87 | TARBP2 (0.55) | TARBP2PDCD4ALDH1A1KDM4EKMT2A | |
| SCHEMBL29158624 | 0.86 | TARBP2 (0.65) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL7694080 | 0.85 | IKBKB (0.55) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL7695341 | 0.84 | TARBP2 (0.49) | TARBP2IKBKBPDCD4ALDH1A1KDM4E | |
| SCHEMBL30106264 | 0.84 | TARBP2 (0.49) | TARBP2IKBKBPDCD4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |