Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 7/20 | 0.53 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701393 | 0.90 | TARBP2 (0.52) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL29158624 | 0.90 | TARBP2 (0.65) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7698153 | 0.88 | TARBP2 (0.52) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7701292 | 0.87 | TARBP2 (0.67) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7694392 | 0.87 | TARBP2 (0.51) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7699330 | 0.87 | KDM4E (0.53) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7699428 | 0.85 | TARBP2 (0.53) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7697412 | 0.85 | TARBP2 (0.49) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL29158601 | 0.85 | TARBP2 (0.49) | IKBKBTARBP2PDCD4KMT2AKDM4E | |
| SCHEMBL7695426 | 0.85 | GAA (0.49) | IKBKBTARBP2PDCD4KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |