SCHEMBL769948

SCHEMBL769948

CC(C)(C)CCCSCCC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
EPHX2 P34913 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014070 0.87 HDAC1 (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL12775715 0.81 EPHX2 (0.39) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL22615683 0.79 TDP1 (0.40) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL5014073 0.79 LMNA (0.56) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL770495 0.79 HDAC3 (0.35) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL22869218 0.79 EPHX2 (0.41) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL23768553 0.78 HDAC3 (0.38) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1880277 0.77 EPHX2 (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL13892879 0.77 TSHR (0.42) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL10250201 0.77 EPHX2 (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217921-B2 Resist underlayer film forming composition containing silicon having sulfide bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-22 US disclosed
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND SMC3, SRSF3, SRSF9 HDAC3 905/4885HDAC1 702/4885HDAC2 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.