Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8026312 | 0.80 | TBXAS1 (0.43) | PKMMAPK1TBXAS1KDM1AMEN1 | |
| SCHEMBL3042625 | 0.73 | LTA4H (0.57) | PTGER4LTA4H | |
| SCHEMBL3039545 | 0.72 | LTA4H (0.54) | PTGER4LTA4H | |
| SCHEMBL3042988 | 0.72 | LTA4H (0.53) | MAPK1PTGER4LMNALTA4H | |
| SCHEMBL22048755 | 0.71 | KDM1A (0.55) | PKMMAPK1TBXAS1KDM1AMEN1 | |
| SCHEMBL3819400 | 0.71 | GBA2 (0.52) | PKMMAPK1 | |
| SCHEMBL16180269 | 0.71 | GBA2 (0.52) | PKMMAPK1 | |
| SCHEMBL3826442 | 0.70 | HRH3 (0.62) | PKMESR1MAPK1TBXAS1KDM1A | |
| SCHEMBL1979241 | 0.70 | HRH3 (0.70) | PKMMAPK1TBXAS1KDM1AMEN1 | |
| SCHEMBL19047914 | 0.70 | HRH1 (0.60) | PKMKDM1AHRH2HRH1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802910-B1 | ESTROGEN AGONISTS/ANTAGONISTS | PFIZER (US) | 2002-03-13 | — | — | EP | disclosed |