Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699647 | 0.87 | RPS6KB2 (0.73) | PDGFRBPDGFRARPS6KB2NPC1NPY5R | |
| SCHEMBL7693473 | 0.75 | SNCA (0.38) | PDGFRBPDGFRARPS6KB2GPBAR1TDP1 | |
| SCHEMBL7693469 | 0.75 | CA2 (0.36) | PDGFRBPDGFRACYP2A6NPY5RGPBAR1 | |
| SCHEMBL7691149 | 0.74 | KDM4E (0.62) | RPS6KB2NPC1NQO2TDP1SMN1; SMN2 | |
| SCHEMBL15665538 | 0.74 | HPGD (0.76) | NPC1TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7693467 | 0.74 | SNCA (0.38) | PDGFRBPDGFRARPS6KB2GPBAR1TDP1 | |
| SCHEMBL14800061 | 0.72 | PDGFRB (0.56) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 | |
| SCHEMBL14211960 | 0.71 | KDM4E (0.59) | RPS6KB2NPC1NQO2TDP1SMN1; SMN2 | |
| SCHEMBL2869861 | 0.70 | ADORA2A (0.41) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 | |
| SCHEMBL7468435 | 0.70 | NPC1 (0.67) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |