Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334467 | 0.81 | KDM4E (0.62) | ALDH1A1ALOX15HSD17B10HTTMAPT | |
| SCHEMBL5716842 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CTNNB1WNT3AKMT2AMEN1 | |
| SCHEMBL7702809 | 0.79 | CTNNB1 (0.52) | ALDH1A1RXRBRXRARXRGCTNNB1 | |
| SCHEMBL10353455 | 0.78 | HDAC3 (0.49) | ALDH1A1HSD17B10MAPTHPGDL3MBTL1 | |
| SCHEMBL10854918 | 0.77 | HRH3 (0.65) | ALDH1A1ALOX15CTNNB1WNT3ARAB9A | |
| SCHEMBL11321136 | 0.77 | MAPT (0.50) | ALDH1A1ALOX15TSHRMAPTGAA | |
| SCHEMBL9667044 | 0.77 | ALDH1A1 (0.61) | ALDH1A1RXRBRXRARXRGCTNNB1 | |
| Hydrochloric Acid SCHEMBL11334584 | 0.76 | MAPT (0.49) | ALDH1A1ALOX15TSHRMAPTGAA | |
| Hydrochloric Acid SCHEMBL10851220 | 0.76 | ALDH1A1 (0.65) | ALDH1A1ALOX15HSD17B10RAB9AHTT | |
| SCHEMBL11194481 | 0.76 | ALDH1A1 (0.56) | ALDH1A1RXRBRXRARXRGCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024630-A1 | PHARMACEUTICAL COMPOUNDS USEFUL AS MODULATORS OF ENDOCANNABINOID-MEDIATED RESPONSE | ELI LILLY AND COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |