Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667044 | 0.96 | ALDH1A1 (0.61) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL19919810 | 0.92 | KDM4E (0.55) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL22013187 | 0.86 | KDM4E (0.49) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL20438663 | 0.86 | KDM4E (0.49) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL4066466 | 0.84 | KDM4E (0.47) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL13676343 | 0.84 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL13676336 | 0.82 | KDM4E (0.45) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL7699711 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAAKMT2AMEN1HTT | |
| SCHEMBL13676320 | 0.79 | HDAC6 (0.46) | ALDH1A1GAAKDM4EDBHRECQL | |
| SCHEMBL20932779 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014119617-A1 | AMIDINE COMPOUND AND SALT THEREOF | 富山化学工業株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8420145-B2 | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |
| EP-1337501-B1 | PROCESS FOR PREPARING 1-INDANONES | AKZO NOBEL NV (NL) | 2006-12-20 | — | — | EP | disclosed |
| EP-1337501-A1 | PROCESS FOR PREPARING 1-INDANONES | Akzo Nobel N.V. (NL) | 2003-08-27 | — | — | EP | disclosed |
| US-6548710-B2 | Reacting ketone compound with chlorinating agent, followed by reaction with a friedel-crafts catalyst to produce 1-indanone compound | AKZO NOBEL N.V. (NL) | 2003-04-15 | — | — | US | disclosed |
| US-20020077507-A1 | Process for preparing 1-indanones | AKZO NOBEL N.V. (NL) | 2002-06-20 | — | — | US | disclosed |
| WO-2002036537-A1 | PROCESS FOR PREPARING 1-INDANONES | AKZO NOBEL N.V. (NL) | 2002-05-10 | — | — | WO | disclosed |
| EP-0273647-B1 | COUMARAN DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4857516-A | Coumaran derivatives and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0273647-A1 | Coumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | TAS2R10, TAS2R41, TAS2R30 | ALDH1A1 408/4885GAA 1012/4885KDM4E 2993/4885 |
| US-20020077507-A1 | Process for preparing 1-indanones | CYP1A1, CYP2F1, CYP1B1 | ALDH1A1 240/4885GAA 4253/4885KDM4E 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.