Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696968 | 0.85 | PLA2G2A (0.74) | PLA2G2APLA2G1B | |
| SCHEMBL7952979 | 0.80 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL7965041 | 0.80 | PLA2G2A (0.80) | PLA2G2APLA2G1B | |
| SCHEMBL8235994 | 0.80 | PLA2G2A (0.67) | PLA2G2APLA2G1BTSHRMAPK1KMT2A | |
| SCHEMBL7953087 | 0.78 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL9551975 | 0.75 | HTR6 (0.55) | PLA2G2APLA2G1BTSHRMAPK1KMT2A | |
| SCHEMBL14400654 | 0.75 | PLA2G2A (0.58) | PLA2G2APLA2G1BTSHRMAPK1KMT2A | |
| SCHEMBL10050594 | 0.75 | PLA2G2A (0.58) | PLA2G2APLA2G1BTSHRMAPK1KMT2A | |
| SCHEMBL7694912 | 0.75 | PLA2G2A (0.77) | PLA2G2APLA2G1B | |
| SCHEMBL344897 | 0.75 | PLA2G2A (0.84) | PLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |