SCHEMBL7699747

SCHEMBL7699747

Cn1nc(CCO)cc1C1NCCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRCP P42785 7/20 0.46
RECQL P46063 1/20 0.45
GAA P10253 1/20 0.45
GID4 Q8IVV7 1/20 0.42
KDM1A O60341 2/20 0.39
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLC22A1 O15245 1/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DRD1 P21728 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699653 0.90 PRCP (0.48) PRCPRECQLGAAGID4KDM1A
SCHEMBL7697968 0.84 PRCP (0.47) PRCPRECQLGAAGID4KDM1A
SCHEMBL7702576 0.83 PRCP (0.43) PRCPRECQLGAAGID4MAPT
SCHEMBL5023205 0.80 PRCP (0.55) PRCPRECQLGAAGID4KDM1A
SCHEMBL5023198 0.80 PRCP (0.55) PRCPRECQLGAAGID4KDM1A
SCHEMBL7704233 0.79 PRCP (0.41) PRCPRECQLGAAGID4SMN1; SMN2
SCHEMBL7704232 0.79 PRCP (0.41) PRCPRECQLGAAGID4SMN1; SMN2
SCHEMBL7702900 0.71 PRCP (0.34) PRCPDRD1
SCHEMBL8584880 0.71 PRCP (0.39) PRCP
SCHEMBL8508972 0.69 PRCP (0.53) PRCPRECQLGAAGID4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901488-B1 2,4-DIAMINOPYRIMIDINE DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2002-11-06 EP disclosed