Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699747 | 0.90 | PRCP (0.46) | PRCPRECQLGAAGID4KDM1A | |
| SCHEMBL7697968 | 0.86 | PRCP (0.47) | PRCPRECQLGAAGID4KDM1A | |
| SCHEMBL7702576 | 0.85 | PRCP (0.43) | PRCPRECQLGAAGID4MAPT | |
| SCHEMBL5023198 | 0.82 | PRCP (0.55) | PRCPRECQLGAAGID4KDM1A | |
| SCHEMBL5023205 | 0.82 | PRCP (0.55) | PRCPRECQLGAAGID4KDM1A | |
| SCHEMBL7704233 | 0.81 | PRCP (0.41) | PRCPRECQLGAAGID4SMN1; SMN2 | |
| SCHEMBL7704232 | 0.81 | PRCP (0.41) | PRCPRECQLGAAGID4SMN1; SMN2 | |
| SCHEMBL8508348 | 0.78 | SIGMAR1 (0.32) | PRCPMAPTMEN1KMT2AOPRM1 | |
| SCHEMBL8508972 | 0.71 | PRCP (0.53) | PRCPRECQLGAAGID4MAPT | |
| SCHEMBL8611806 | 0.70 | HHAT (0.39) | PRCPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |