Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023205 | 0.75 | PRCP (0.55) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL5023198 | 0.75 | PRCP (0.55) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL7699653 | 0.71 | PRCP (0.48) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL1668148 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL30721685 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL29478499 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL325083 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL327233 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL12046710 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL7699747 | 0.69 | PRCP (0.46) | PRCPGAARECQLGID4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |