Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700148 | 1.00 | SIRT2 (0.43) | SIRT2TBXAS1GPR52NMBR | |
| SCHEMBL28361768 | 0.87 | SIRT2 (0.42) | SIRT2NMBR | |
| SCHEMBL9263513 | 0.85 | MAPT (0.46) | SIRT2NMBR | |
| SCHEMBL9263509 | 0.85 | MAPT (0.46) | SIRT2NMBR | |
| SCHEMBL1040511 | 0.82 | SIRT2 (0.49) | SIRT2NMBR | |
| SCHEMBL7972750 | 0.81 | SIRT2 (0.48) | SIRT2NMBR | |
| SCHEMBL1041256 | 0.81 | GPR52 (0.48) | SIRT2GPR52 | |
| SCHEMBL1041255 | 0.81 | GPR52 (0.48) | SIRT2GPR52 | |
| SCHEMBL877785 | 0.80 | SIRT2 (0.46) | SIRT2NMBR | |
| SCHEMBL1040962 | 0.80 | SIRT2 (0.46) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355665-B1 | ANTIHISTAMINES, ANTIALLERGENS AND IRRITABLE BOWEL SYNDROME. | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |