Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609954 | 0.89 | SIGMAR1 (0.50) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 | |
| SCHEMBL10481909 | 0.85 | SIGMAR1 (0.48) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 | |
| SCHEMBL10639770 | 0.85 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 | |
| SCHEMBL10639766 | 0.85 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 | |
| SCHEMBL3047898 | 0.80 | CYP1A2 (0.62) | CYP1A2CYP2C19CYP2D6NQO2CYP2C9 | |
| SCHEMBL8375777 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2D6NQO2CYP2C9 | |
| SCHEMBL7948847 | 0.80 | MTNR1A (0.49) | CYP1A2CYP2C19CYP2D6NQO2CYP2C9 | |
| SCHEMBL143458 | 0.80 | MTNR1A (0.49) | CYP1A2CYP2C19CYP2D6NQO2CYP2C9 | |
| SCHEMBL5516425 | 0.80 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 | |
| SCHEMBL29891134 | 0.80 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6SLC18A2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021405-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2002-09-25 | — | — | EP | claimed |
| CN-116507633-A | Glycosylated IL-2 proteins and uses thereof | 阿森迪斯药物肿瘤股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116133676-A | IL-2 sequences and uses thereof | 阿森迪斯药物肿瘤股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-1204262-C | Method for producing optically active amines | BASF AG (DE) | 2005-06-01 | — | — | CN | disclosed |
| CN-1195764-C | Transition metal complex, preparation method and use thereof | BASF AG (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1496991-A | Chirality monophosphorous compound and its transition metal compound | — | 2004-05-19 | — | — | CN | disclosed |
| CN-1493576-A | Chiral diphosphorus compound and its transition metal compounding product | — | 2004-05-05 | — | — | CN | disclosed |
| CN-1131233-C | Carbohydrate derivatives and their solid-phase synthesis | BASF AG (DE) | 2003-12-17 | — | — | CN | disclosed |
| CN-1399687-A | Process for preparing optically active amines | BASF AG (DE) | 2003-02-26 | — | — | CN | disclosed |
| CN-1330074-A | Transition metal complex, preparation method and use thereof | BASF AG (DE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1072227-C | Optically active diphosphine ligands | BASF AG (DE) | 2001-10-03 | — | — | CN | disclosed |
| CN-1219937-A | Carbohydrate derivatives and their solid-phase synthesis | BASF AG (DE) | 1999-06-16 | — | — | CN | disclosed |
| CN-1202492-A | Optically active diphosphine ligands | BASF AG (DE) | 1998-12-23 | — | — | CN | disclosed |
| CN-1105354-A | Novel alkamine derivative and slat of same | YAMANOUCHI PHARMA CO LTD (JP) | 1995-07-19 | — | — | CN | disclosed |
| US-4783562-A | Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-08 | — | — | US | disclosed |
| EP-0061029-B1 | PROCESS FOR THE PREPARATION OF TRICHLOROMETHYL-SUBSTITUTED AROMATIC COMPOUNDS | BAYER AG (DE) | 1986-01-08 | — | — | EP | disclosed |