Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 14/20 | 0.64 |
| ▸ | EDNRA | P25101 | 6/20 | 0.54 |
| ▸ | EDNRB | P24530 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060092 | 0.89 | EDNRB (0.67) | DHPSEDNRAEDNRB | |
| SCHEMBL4061147 | 0.89 | DHPS (0.80) | DHPSEDNRAEDNRB | |
| SCHEMBL7209693 | 0.87 | DHPS (0.58) | DHPS | |
| SCHEMBL7700296 | 0.85 | EDNRA (0.57) | DHPSEDNRAEDNRB | |
| SCHEMBL4059948 | 0.84 | EDNRA (0.63) | DHPSEDNRAEDNRB | |
| SCHEMBL4062792 | 0.84 | EDNRB (0.63) | DHPSEDNRAEDNRB | |
| SCHEMBL8323076 | 0.83 | DHPS (0.56) | DHPSEDNRAEDNRB | |
| SCHEMBL4064951 | 0.83 | EDNRB (0.70) | DHPSEDNRAEDNRB | |
| SCHEMBL5107964 | 0.82 | EDNRB (0.64) | DHPSEDNRAEDNRB | |
| SCHEMBL4064097 | 0.80 | DHPS (0.74) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |