Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901444 | 0.85 | ALDH1A1 (0.31) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5490363 | 0.83 | SRC (0.35) | SRCLMNAMEN1THRBBLM | |
| SCHEMBL6851211 | 0.82 | TDP1 (0.41) | LMNAMEN1THRBBLMKMT2A | |
| SCHEMBL28690581 | 0.79 | SRC (0.37) | SRCLMNAMEN1THRBBLM | |
| SCHEMBL955154 | 0.78 | ERN1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL955841 | 0.78 | ALDH1A1 (0.40) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL952797 | 0.78 | ESR1 (0.36) | ALDH1A1GAA | |
| SCHEMBL954498 | 0.78 | CYP3A4 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8237028 | 0.78 | — | — | |
| SCHEMBL28775677 | 0.78 | GABRA1 (0.45) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355826-B1 | HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-03-12 | — | — | US | disclosed |
| US-6252009-B1 | CROSSLINKING ACRYLONITRILE WITH DIISOCYANATE | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-06-26 | — | — | US | disclosed |
| EP-0903338-A2 | Synthesis of stable nitrile oxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-24 | — | — | EP | disclosed |