SCHEMBL7700313

SCHEMBL7700313

CCCCCCC(=O)CC(CCc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.48
MMP2 P08253 2/20 0.47
MMP3 P08254 2/20 0.47
S1PR2 O95136 2/20 0.47
S1PR1 P21453 2/20 0.47
EPHX2 P34913 1/20 0.47
S1PR3 Q99500 1/20 0.46
HPGD P15428 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGES O14684 2/20 0.45
ALOX5 P09917 2/20 0.45
PPARG P37231 2/20 0.45
TRPV1 Q8NER1 1/20 0.45
CAPN1 P07384 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8473749 0.87 TRPA1 (0.54) TRPA1TRPV1
SCHEMBL8905851 0.84 MMP2 (0.55) MMP2MMP3S1PR2S1PR1PTGES
SCHEMBL7077500 0.84 MMP2 (0.55) MMP2MMP3S1PR2S1PR1PTGES
SCHEMBL28210404 0.84 MMP2 (0.55) MMP2MMP3S1PR2S1PR1PTGES
SCHEMBL8905261 0.84 MMP2 (0.55) MMP2MMP3S1PR2S1PR1PTGES
SCHEMBL1716640 0.84 MMP2 (0.55) MMP2MMP3S1PR2S1PR1PTGES
SCHEMBL8474027 0.84 TRPA1 (0.58) TRPA1TRPV1
SCHEMBL8904812 0.82 MMP2 (0.56) MMP2MMP3HPGDPTGESALOX5
SCHEMBL473644 0.81 MMP2 (0.61) MMP2MMP3PTGESALOX5PPARG
SCHEMBL9277107 0.80 HDAC8 (0.49) MMP2MMP3S1PR2S1PR1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6369248-B1 HYDROXY ESTERS FOR PERFUMES GIVAUDAN SA (CH) 2002-04-09 US disclosed
EP-0989970-A1 FRAGRANCE PRECURSOR COMPOUNDS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2000-04-05 EP disclosed
WO-1998058899-A1 FRAGRANCE PRECURSOR COMPOUNDS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-12-30 WO disclosed