Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.63 |
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | SHBG | P04278 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702771 | 0.90 | AR (0.66) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL7704209 | 0.85 | AR (0.60) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL7704185 | 0.83 | AR (0.62) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL6462161 | 0.83 | AR (0.74) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL13216965 | 0.82 | AR (0.64) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL13216966 | 0.81 | AR (0.71) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL2834009 | 0.81 | AR (0.71) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL7885462 | 0.78 | AR (0.72) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL6464133 | 0.78 | AR (0.72) | ARPGRNR3C2SERPINA6SHBG | |
| SCHEMBL2965005 | 0.78 | AR (0.63) | ARPGRNR3C2SERPINA6SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |