Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.41 |
| ▸ | SHBG | P04278 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702771 | 0.87 | AR (0.66) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL7700533 | 0.85 | AR (0.63) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL7704185 | 0.81 | AR (0.62) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL6462161 | 0.81 | AR (0.74) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL13216965 | 0.80 | AR (0.64) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL2965005 | 0.79 | AR (0.63) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL2834009 | 0.79 | AR (0.71) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL13216966 | 0.79 | AR (0.71) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL24102452 | 0.77 | AR (0.70) | ARMAPTPGRNR3C2ALDH1A1 | |
| SCHEMBL24102494 | 0.76 | AR (1.00) | ARMAPTPGRNR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |