Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.71 |
| ▸ | PGR | P06401 | 8/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.51 |
| ▸ | SHBG | P04278 | 3/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13216966 | 1.00 | AR (0.71) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6462161 | 0.91 | AR (0.74) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL13216965 | 0.86 | AR (0.64) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7702771 | 0.84 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL2832494 | 0.84 | ALDH1A1 (0.69) | PGRSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL13216858 | 0.84 | ALDH1A1 (0.69) | PGRSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24103284 | 0.83 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL14342101 | 0.83 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL24102494 | 0.83 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL223290 | 0.83 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204497-A1 | Process For The Preparation of 7 alpha-Methylsteroids | N.V. ORGANON | 2010-08-12 | — | — | US | disclosed |
| EP-1470151-B1 | PROCESS FOR THE PREPARATION OF 7-ALPHA-METHYLSTEROIDS | ORGANON NV (NL) | 2009-12-30 | — | — | EP | disclosed |
| US-20050090476-A1 | Process for the preparation of 7alpha-methylsteroids | MERCK SHARP & DOHME B.V. (NL) | 2005-04-28 | — | — | US | disclosed |
| EP-1470151-A1 | PROCESS FOR THE PREPARATION OF 7-ALPHA-METHYLSTEROIDS | Akzo Nobel N.V. (NL) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003059931-A1 | PROCESS FOR THE PREPARATION OF 7α-METHYLSTEROIDS | AKZO NOBEL N.V. (NL) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090476-A1 | Process for the preparation of 7alpha-methylsteroids | CYP17A1, CYP21A2, HSD17B7 | AR 171/4885PGR 230/4885NR3C2 14/4885 |
| US-20100204497-A1 | Process For The Preparation of 7 alpha-Methylsteroids | CYP17A1, CYP21A2, HSD17B7 | AR 171/4885PGR 229/4885NR3C2 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.