Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 12/20 | 0.42 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700540 | 0.88 | EDNRB (0.38) | DHPSEDNRBEDNRA | |
| SCHEMBL5654649 | 0.79 | DHPS (0.62) | DHPSEDNRBEDNRA | |
| SCHEMBL4064364 | 0.78 | DHPS (0.56) | DHPS | |
| SCHEMBL7700003 | 0.77 | DHPS (0.46) | DHPS | |
| SCHEMBL6961036 | 0.75 | DHPS (0.51) | DHPSEDNRBEDNRA | |
| SCHEMBL4060142 | 0.74 | DHPS (0.54) | DHPSEDNRBEDNRA | |
| SCHEMBL5765225 | 0.74 | DHPS (0.47) | DHPS | |
| Tetrahydrofuran SCHEMBL25230185 | 0.74 | DHPS (0.55) | DHPSEDNRBEDNRA | |
| SCHEMBL5654640 | 0.71 | EDNRA (0.51) | DHPSEDNRBEDNRA | |
| SCHEMBL25234371 | 0.71 | EDNRA (0.50) | DHPSEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |