Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978906 | 0.85 | CYP2A6 (0.50) | NR1H2PTGS2CYP2A6 | |
| SCHEMBL4281566 | 0.83 | CYP2A6 (0.48) | NPC1RAB9APTGS2MEN1KMT2A | |
| SCHEMBL7700098 | 0.82 | GSTP1 (0.50) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL7703864 | 0.81 | GSTP1 (0.49) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL7700044 | 0.81 | GSTP1 (0.49) | GSTP1LTA4HTSHRHSP90AA1NR1H2 | |
| SCHEMBL1646823 | 0.80 | ABL1 (0.50) | TSHRNPC1RAB9APTGS2SMN1; SMN2 | |
| SCHEMBL7703851 | 0.77 | GSTP1 (0.49) | GSTP1LTA4HTSHRNSD2HSP90AA1 | |
| SCHEMBL435264 | 0.77 | CYP1A2 (0.42) | TSHRNPC1RAB9APTGS2SMN1; SMN2 | |
| SCHEMBL9685460 | 0.76 | DPP4 (0.44) | LTA4HTSHRNR1H2PTGS2GAA | |
| SCHEMBL3656937 | 0.74 | PARP10 (0.50) | GSTP1HSP90AA1SCN4AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |