Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621655 | 0.85 | ALDH1A1 (0.39) | NPC1RAB9APTGS2 | |
| SCHEMBL185890 | 0.85 | ALDH1A1 (0.41) | PTGS2 | |
| SCHEMBL8571095 | 0.85 | ABL1 (0.50) | LTA4HTSHRNPC1RAB9APTGS2 | |
| SCHEMBL6573031 | 0.81 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL7700568 | 0.81 | GSTP1 (0.50) | GSTP1LTA4HTSHRNCOA1NCOA3 | |
| SCHEMBL7700098 | 0.81 | GSTP1 (0.50) | GSTP1LTA4HTSHRNCOA1NCOA3 | |
| SCHEMBL9559546 | 0.80 | NPC1 (0.47) | GSTP1LTA4HNPC1RAB9AFFAR4 | |
| SCHEMBL7700044 | 0.79 | GSTP1 (0.49) | GSTP1LTA4HTSHRNCOA1NCOA3 | |
| SCHEMBL28716480 | 0.79 | CYP1A2 (0.50) | TSHRNPC1RAB9APTGS2 | |
| SCHEMBL9559722 | 0.79 | PTGS2 (0.40) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |