Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699874 | 0.92 | MAPT (0.66) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7698848 | 0.89 | ALDH1A1 (0.68) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7700870 | 0.86 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7696853 | 0.85 | ALDH1A1 (0.62) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7697447 | 0.84 | ALDH1A1 (0.82) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7695231 | 0.83 | ALDH1A1 (0.66) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7695048 | 0.83 | ALDH1A1 (0.66) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7699809 | 0.80 | ALDH1A1 (0.74) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7700945 | 0.80 | ALDH1A1 (0.60) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL7700627 | 0.79 | ALDH1A1 (0.52) | MAPTLMNAALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |