Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699872 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7696848 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7700867 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7701010 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7695046 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7699807 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7700628 | 0.79 | MAPT (0.76) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7695229 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7694366 | 0.77 | MAPT (0.44) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL7700070 | 0.75 | TP53 (0.49) | ALDH1A1KDM4EHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |