Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 17/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698978 | 0.92 | CCR2 (0.47) | SLC2A1CCR2 | |
| SCHEMBL7699814 | 0.89 | CCR2 (0.36) | SLC2A1CCR2 | |
| SCHEMBL7698124 | 0.84 | CCR2 (0.51) | SLC2A1CCR2 | |
| SCHEMBL7697546 | 0.82 | SLC2A1 (0.60) | SLC2A1CCR2KDM4EBRD4ALDH1A1 | |
| SCHEMBL5352889 | 0.80 | CCR2 (0.55) | SLC2A1CCR2 | |
| SCHEMBL7702544 | 0.78 | CCR2 (0.62) | SLC2A1CCR2 | |
| SCHEMBL5358213 | 0.76 | CCR2 (0.53) | SLC2A1CCR2 | |
| SCHEMBL7700232 | 0.75 | SLC2A1 (0.69) | SLC2A1CCR2 | |
| SCHEMBL5352711 | 0.73 | CCR2 (0.53) | SLC2A1CCR2 | |
| SCHEMBL7702546 | 0.70 | SLC2A1 (0.52) | SLC2A1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |