Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703003 | 0.91 | CCR2 (0.62) | CCR2SLC2A1 | |
| SCHEMBL7700232 | 0.90 | SLC2A1 (0.69) | CCR2SLC2A1 | |
| SCHEMBL7695531 | 0.90 | CCR2 (0.52) | CCR2SLC2A1 | |
| SCHEMBL7702941 | 0.90 | CCR2 (0.51) | CCR2SLC2A1 | |
| SCHEMBL7699076 | 0.88 | CCR2 (0.52) | CCR2 | |
| SCHEMBL7700299 | 0.88 | CCR2 (0.49) | CCR2SLC2A1 | |
| SCHEMBL7697546 | 0.88 | SLC2A1 (0.60) | CCR2SLC2A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7698124 | 0.87 | CCR2 (0.51) | CCR2SLC2A1 | |
| SCHEMBL7701596 | 0.87 | CCR2 (0.51) | CCR2 | |
| SCHEMBL7695961 | 0.87 | HTR1D (0.54) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |