Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695015 | 0.86 | KCNA5 (0.37) | CXCR2NQO2KCNA5MALT1MAPT | |
| SCHEMBL7700721 | 0.86 | CXCR2 (0.35) | CXCR2NQO2KCNA5MALT1MAPT | |
| Hydrochloric Acid SCHEMBL7702260 | 0.84 | PARP1 (0.36) | NQO2LMNATP53PARP1HTT | |
| Hydrochloric Acid SCHEMBL7696592 | 0.83 | RAD52 (0.39) | PARP1KDM4EHTT | |
| SCHEMBL7702982 | 0.82 | PARP1 (0.43) | MAPTPOLBTP53PARP1HTT | |
| Hydrochloric Acid SCHEMBL7697554 | 0.81 | PARP1 (0.42) | MAPTPOLBTP53PARP1HTT | |
| SCHEMBL7872528 | 0.81 | NQO2 (0.37) | CXCR2NQO2KCNA5MALT1MAPT | |
| SCHEMBL7701178 | 0.78 | PARP1 (0.41) | MAPTPOLBTP53PARP1HTT | |
| SCHEMBL7697131 | 0.77 | PARP1 (0.46) | MAPTHPGDPOLBTP53PARP1 | |
| SCHEMBL7700738 | 0.76 | PARP1 (0.37) | MAPTPOLBTP53PARP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |