Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700721 | 0.81 | CXCR2 (0.35) | NQO2KCNA5CXCR2MALT1LMNA | |
| SCHEMBL28027633 | 0.72 | KCNA5 (0.56) | NQO2KCNA5CXCR2MALT1GAA | |
| SCHEMBL14691066 | 0.67 | DRD2 (0.45) | NQO2KCNA5CXCR2MALT1LMNA | |
| SCHEMBL1657927 | 0.67 | ESRRG (0.56) | KCNA5CXCR2MALT1GAAHPGD | |
| SCHEMBL9540574 | 0.67 | KCNA5 (0.58) | NQO2KCNA5CXCR2MALT1LMNA | |
| SCHEMBL4059012 | 0.66 | HPGD (0.56) | KCNA5MALT1GAAHPGDMAPT | |
| SCHEMBL14691000 | 0.66 | KCNA5 (0.46) | NQO2KCNA5CXCR2MALT1HPGD | |
| SCHEMBL2299797 | 0.65 | CXCR2 (0.42) | NQO2KCNA5CXCR2MALT1BCHE | |
| SCHEMBL14690580 | 0.65 | CRBN (0.51) | KCNA5CXCR2MALT1HPGDPOLB | |
| SCHEMBL9743749 | 0.65 | KCNA5 (0.56) | NQO2KCNA5CXCR2MALT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |