Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7700757 | 0.84 | KCNH2 (0.44) | CYP1A2CYP2C19 | |
| Fumaric Acid SCHEMBL7700761 | 0.84 | KCNH2 (0.44) | CYP1A2CYP2C19 | |
| SCHEMBL8286567 | 0.83 | MEN1 (0.36) | MEN1KMT2ACYP1A2CYP2C19KDM4E | |
| SCHEMBL10589521 | 0.65 | CNR2 (0.37) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7701317 | 0.65 | KCNH2 (0.47) | CYP1A2CYP2C19KDM4EALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7702535 | 0.64 | KCNH2 (0.47) | CYP1A2CYP2C19KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL7700726 | 0.63 | CYP2D6 (0.44) | CYP1A2GAACYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7700691 | 0.61 | KCNH2 (0.48) | CYP1A2CYP2C19KDM4EALDH1A1HPGD | |
| SCHEMBL2008744 | 0.61 | KCNH2 (0.47) | CYP1A2CYP2C19KDM4EALDH1A1HPGD | |
| Fumaric Acid SCHEMBL10921842 | 0.59 | HRH1 (0.47) | MEN1KMT2AKDM4EALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-B1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2002-07-03 | — | — | EP | disclosed |
| US-6265445-B1 | CARDIOVASCULAR DISORDERS | GYOGYSZERKUTATO INTEZET KFT (HU) | 2001-07-24 | — | — | US | disclosed |