Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700759 | 0.83 | MEN1 (0.35) | MEN1KMT2AHPGDCYP1A2CYP2C19 | |
| Fumaric Acid SCHEMBL7700757 | 0.67 | KCNH2 (0.44) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fumaric Acid SCHEMBL7700761 | 0.67 | KCNH2 (0.44) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10589521 | 0.65 | CNR2 (0.37) | ALDH1A1HCAR2 | |
| Hydrochloric Acid SCHEMBL8216596 | 0.65 | KCNH2 (0.50) | HPGDKCNH2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8205350 | 0.64 | KCNH2 (0.49) | HPGDKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8213885 | 0.63 | RORC (0.41) | MEN1KMT2AHPGDKCNH2CYP1A2 | |
| Fumaric Acid SCHEMBL7316884 | 0.61 | SLC6A9 (0.65) | MEN1KMT2AHPGDSLC6A9CYP3A4 | |
| Maleic Acid SCHEMBL7316880 | 0.61 | SLC6A9 (0.65) | MEN1KMT2AHPGDSLC6A9CYP3A4 | |
| SCHEMBL6140360 | 0.61 | KCNH2 (0.50) | HPGDKCNH2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | disclosed |