Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094158 | 0.87 | LMNA (0.56) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7094245 | 0.85 | LMNA (0.54) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9640407 | 0.79 | LMNA (0.68) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL3373766 | 0.79 | LMNA (0.68) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL3460771 | 0.78 | SMN1; SMN2 (0.95) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL3984004 | 0.77 | LMNA (0.69) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL14517020 | 0.77 | HSD17B10 (0.52) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9818668 | 0.77 | CNR1 (0.70) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10083664 | 0.76 | LMNA (1.00) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL300331 | 0.75 | CNR1 (0.72) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |