Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702473 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7700429 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7696766 | 0.89 | ALDH1A1 (0.40) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7694566 | 0.88 | UBE2N (0.42) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7694405 | 0.86 | S1PR1 (0.38) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7696676 | 0.85 | TP53 (0.43) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7695041 | 0.84 | TP53 (0.47) | ALDH1A1TSHRHTTTP53MAPT | |
| SCHEMBL7702583 | 0.84 | POLB (0.42) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7704672 | 0.83 | MAPT (0.45) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7695046 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |