Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699756 | 0.95 | EPHX2 (0.48) | EPHX2TRPV1DGAT1PTGESCNR1 | |
| SCHEMBL7701384 | 0.95 | EPHX2 (0.51) | EPHX2TRPV1DGAT1PTGESCNR1 | |
| SCHEMBL7700128 | 0.92 | EPHX2 (0.49) | EPHX2DGAT1PTGESCNR1CNR2 | |
| SCHEMBL7701962 | 0.92 | TAOK1 (0.54) | EPHX2DGAT1PTGESCNR1CNR2 | |
| SCHEMBL7703699 | 0.92 | ALDH1A1 (0.51) | EPHX2TRPV1DGAT1PTGESCNR1 | |
| SCHEMBL7701450 | 0.92 | EPHX2 (0.48) | EPHX2DGAT1PTGESCNR1CNR2 | |
| SCHEMBL7696456 | 0.92 | MAPT (0.51) | EPHX2DGAT1RAB9AMEN1TP53 | |
| SCHEMBL7693795 | 0.91 | KDM4E (0.51) | EPHX2DGAT1PTGESCNR1CNR2 | |
| SCHEMBL7693770 | 0.90 | TSHR (0.50) | EPHX2NPC1RAB9AMEN1TP53 | |
| SCHEMBL7696332 | 0.89 | PTGES (0.49) | EPHX2DGAT1PTGESCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |