SCHEMBL7701

SCHEMBL7701

Fc1cc(Br)ccc1CCl

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.46
TRAP1 Q12931 3/20 0.41
HSP90AA1 P07900 2/20 0.41
HSP90AB1 P08238 1/20 0.41
KDM1A O60341 3/20 0.41
KDM1B Q8NB78 1/20 0.41
CHRM5 P08912 1/20 0.41
AKR1B1 P15121 3/20 0.40
PDPK1 O15530 1/20 0.40
DGAT1 O75907 1/20 0.39
HSP90B1 P14625 2/20 0.39
NAAA Q02083 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30789000 1.00 PYCR1 (0.46) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
Methane SCHEMBL27753799 0.98 PYCR1 (0.45) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL27753798 0.83 PDPK1 (0.44) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL20560539 0.82 DPP4 (0.40) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL29393338 0.79 PYCR1 (0.47) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL20465750 0.79 PYCR1 (0.47) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL15806743 0.79 PYCR1 (0.47) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL308050 0.79 PYCR1 (0.47) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL31448605 0.79 PYCR1 (0.47) PYCR1TRAP1HSP90AA1HSP90AB1KDM1A
SCHEMBL1561687 0.78 CYP2A6 (0.35) PYCR1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067770-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SK PUCORE CO., LTD. (KR) 2024-02-29 US claimed
EP-4209526-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SKC Co., Ltd. (KR) 2023-07-12 EP claimed
CN-115989280-A Polythiol composition and optical polymerizable composition comprising the same SKC株式会社 2023-04-18 CN claimed
CN-119569735-A Heteroaryl compounds, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2025-03-07 CN disclosed
US-20250034150-A1 BTK INHIBITORS BIOGEN MA INC. 2025-01-30 US disclosed
EP-4429770-A1 BTK INHIBITORS Biogen MA Inc. (US) 2024-09-18 EP disclosed
EP-3455224-B1 SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF BAYER AG (DE) 2024-03-27 EP disclosed
US-20240067770-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SK PUCORE CO., LTD. (KR) 2024-02-29 US disclosed
CN-114029091-B Dual ligand catalytic system for ethylene selective trimerization, preparation method and application thereof 浙江智英石化技术有限公司 2024-01-16 CN disclosed
EP-4209526-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SKC Co., Ltd. (KR) 2023-07-12 EP disclosed
WO-2023086521-A1 BTK INHIBITORS BIOGEN MA INC. (US) 2023-05-19 WO disclosed
CN-100402524-C Synthesis of 8-(4,6-dimethoxy pyrimidine oxy)-2-substituted phentriazine-1-one derivative and its herbicide activity HUZHONG NORMAL UNIV (CN) 2008-07-16 CN disclosed
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2007-10-18 US disclosed
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2007-10-18 US disclosed
WO-2007090826-A1 PIPERIDINE DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 2007-08-16 WO disclosed
CN-1903853-A Synthesis of 8-(4,6-dimethoxy pyrimidine oxy)-2-substituted phentriazine-1-one derivative and its herbicide activity HUZHONG NORMAL UNIV (CN) 2007-01-31 CN disclosed
CN-1832922-A Sulfonyl-substituted N- (biarylmethyl) aminocyclopropanecarboxamides MERCK & CO INC (US) 2006-09-13 CN disclosed
CN-1058594-A Imidazo [4,5-C] pyridines osteoporosis agent AMERICAN HOME PROD (US) 1992-02-12 CN disclosed
US-5081253-A IMIDAZO(4,5-C)PYRIDINES AS ANTIOSTEOPOROTIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1992-01-14 US disclosed
EP-0434405-A1 Imidazo[4,5-c]pyridines as antiosteoporotic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment ZC3HAV1, TPMT, DPP4 PYCR1 394/4885TRAP1 4352/4885HSP90AA1 4268/4885
US-20250034150-A1 BTK INHIBITORS BTK, SYK, LYN PYCR1 4526/4885TRAP1 3894/4885HSP90AA1 1258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.