SCHEMBL308050

SCHEMBL308050

Fc1cc(Br)ccc1CBr

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.47
KDM1A O60341 3/20 0.41
DGAT1 O75907 1/20 0.41
PDPK1 O15530 1/20 0.41
AKR1B1 P15121 1/20 0.41
NAAA Q02083 1/20 0.40
CHRM5 P08912 1/20 0.39
KDM1B Q8NB78 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TRAP1 Q12931 2/20 0.37
HSP90B1 P14625 1/20 0.37
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393338 1.00 PYCR1 (0.47) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL20465750 1.00 PYCR1 (0.47) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL8736491 0.85 CSNK2A1 (0.44) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL2298211 0.82 PDPK1 (0.45) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL15543972 0.82 PYCR1 (0.45) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL31448605 0.81 PYCR1 (0.47) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL138081 0.81 DPP4 (0.41) PYCR1KDM1ADGAT1KDM1BNPC1
SCHEMBL15806743 0.81 PYCR1 (0.47) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL507839 0.79 PYCR1 (0.46) PYCR1KDM1ADGAT1PDPK1AKR1B1
SCHEMBL110765 0.79 PYCR1 (0.46) PYCR1KDM1ADGAT1PDPK1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912847-A Composite coating and application thereof 万华化学集团股份有限公司 2025-05-02 CN claimed
EP-3112340-B1 METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO, AND PRECURSOR OF 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO STELLA PHARMA CORP (JP) 2020-07-15 EP claimed
CN-1047377-C Preparation method of 2-fluor-4-bromotoluene, 2-fluor-4-bromo benzyl bromide and its 2-fluor-4-bromo benzyl bromide FUXIN SPECIAL CHEMICALS CO LTD (CN) 1999-12-15 CN claimed
CN-1157812-A Preparation method of 2-fluor-4-bromotoluene, 2-fluor-4-bromo benzyl bromide and its 2-fluor-4-bromo benzyl bromide FUXIN SPECIAL CHEMICALS CO LTD (CN) 1997-08-27 CN claimed
JP-1203369-A None JP disclosed
CN-122010944-A TBC1D 2-targeted aromatic methyl alkenyl matrine derivative and preparation method and application thereof 广西大学 2026-05-12 CN disclosed
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-23 US disclosed
US-20260070914-A1 SUBSTITUTED PYRROLO[2,1-F][1,2,4]TRIAZIN-2-AMINES AS CDK2 AND CDK4 INHIBITORS INCYTE CORP (US) 2026-03-12 US disclosed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
US-12570642-B2 GLP-IR modulating compounds GILEAD SCIENCES, INC. (US) 2026-03-10 US disclosed
US-20260062420-A1 NOVEL DPP1 INHIBITORS AND USES THEREOF INSMED INC (US) 2026-03-05 US disclosed
EP-4691554-A2 GLP-1R MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 EP disclosed
WO-1986004895-A1 FLUOROBENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-08-28 WO disclosed
US-4581366-A Aldose reductase inhibition by spiro indoline derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-08 US disclosed
US-4567278-A Process for racemizing certain spiro compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US disclosed
EP-0168181-A1 Cyclic amides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-15 EP disclosed
US-4539329-A 7'-Trifluoromethyl-spiro[imidazolidine-4,3'-indoline]-2,2',5-triones as aldose reductase inhibitors IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-09-03 US disclosed
EP-0125090-A2 Indoline derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP disclosed
EP-0115679-A1 Chemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-15 EP disclosed
EP-0101149-A1 Fluoroalkyl indoline derivatives for pharmaceutical use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070914-A1 SUBSTITUTED PYRROLO[2,1-F][1,2,4]TRIAZIN-2-AMINES AS CDK2 AND CDK4 INHIBITORS CCNA1, CCNO, CDK1 PYCR1 989/4885KDM1A 2828/4885DGAT1 3464/4885
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GCGR PYCR1 1507/4885KDM1A 4614/4885DGAT1 1428/4885
US-20260062420-A1 NOVEL DPP1 INHIBITORS AND USES THEREOF DPP4, DPP3, DPP7 PYCR1 3303/4885KDM1A 672/4885DGAT1 2118/4885
US-12570642-B2 GLP-IR modulating compounds GLP1R, GIPR, GPR119 PYCR1 1689/4885KDM1A 2564/4885DGAT1 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.